She was Associate Editor with The Times of India, where she reported and analyzed foreign policy issues for the newspaper from 2004 until 2022.

As Diplomatic Editor, Indrani covered the Ministry of External Affairs (MEA) on her news beat, as well as interpreted and analyzed global trends with an Indian perspective. Earlier, Indrani worked with India Today, a premier news magazine, The Economic Times and The Statesman. 

She graduated from Loreto College, Calcutta University with English honours. Indrani was a Reuters Fellow at Oxford University in 1997. In 2010, Indrani was awarded the Chang Lin-Tien fellowship by the Asia Foundation to study US-China relations at Brookings Institution, Washington DC. She is a Fellow of the Kamalnayan Bajaj Fellowship Class 3 of the Ananta Aspen Centre and a member of Aspen Global Leadership Network.