This White Paper presents the key insights of the 2025 Aspen Healthcare & Quality of Life Program, synthesizing debates and policy reflections emerging from high-level dialogues, expert seminars, and strategic roundtables held throughout the year. It examines the structural challenges facing Romania’s health system, from financing and prevention to hospital governance and digital transformation, while outlining strategic directions for strengthening sustainability, trust, and long-term system resilience in alignment with European developments.